Scientist, Computational Chemistry

Company: Takeda Pharmaceutical
Location: Encinitas
Posted on: May 11, 2022

Job Description:

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's and . I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAt Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.Join Takeda as a Scientist, Computational Chemistry where you will work as part of a multi-disciplinary team of medicinal chemists, structural biologists, and biologists and provide computational expertise to advance drug discovery projects. You will also contribute to drug discovery efforts across various modalities including small molecules, PROTACs, peptides, and more.How you will contribute:

• Participate in the implementation and execution of innovative computational methodologies and tools such as AI, free energy, and cheminformatics approaches to support drug discovery efforts.
• Demonstrate an understanding of computational chemistry principles and their application within a multidisciplinary drug discovery environment.
• Independently design, develop and execute research assignments, contributing to multiple projects.
• Contribute to the identification, development, validation, and implementation of innovative computational approaches that improve research productivity and success.
• Provide important technical knowledge and input to project teams to drive decision making in drug discovery projects.Minimum Requirements/Qualifications:
  • PhD degree in Chemistry, or
  • MS with 6+ years experience, or
  • BS with 8+ years experience
  • Experience with a variety of computational tools and methodology including docking, virtual screening, molecular dynamics, free energy perturbation, homology modeling, quantum mechanics, pharmacophore elucidation, machine learning.
  • Comprehensive experience in data mining and data analysis.
  • Familiarity with organic and synthetic chemistry concepts.
  • Provide project teams with computational strategies to inform, influence, and prioritize designs for potency/selectivity and improve ADME/Tox endpoints.
  • Contribute to the development and deployment of design and/or AI platforms to impact drug discovery.
  • Identify and implement novel computational chemistry algorithms, technologies, and workflows.
  • Familiarity with standard computational chemistry software including Schrodinger Suites, KNIME, and more.
  • Proficiency in scientific scripting and programming languages.What Takeda can offer you:
    • Comprehensive Healthcare: Medical, Dental, and Vision
    • Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
    • Health & Wellness programs including onsite flu shots and health screenings
    • Generous time off for vacation and the option to purchase additional vacation days
    • Community Outreach Programs and company match of charitable contributions
    • Family Planning Support
    • Flexible Work Paths
    • Tuition reimbursementMore about us:At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.Update Takeda U.S. Vaccine Requirement: Absent an approved religious or medical reason, all US office-based and lab-based Takeda employees who work fully on-site or in a hybrid model (as determined by Takeda) must be fully vaccinated to work at a Takeda site or to engage with Takeda colleagues or anyone else on behalf of Takeda. As of the same date, absent an approved religious or medical reason, US field-based employees, employees must be fully vaccinated in order to continue in their current roles. US employees who work at a Takeda manufacturing facility, and those who work at a BioLife center or BioLife lab, may be subject to different guidelines. Candidates are encouraged to speak with their recruiter to seek further information on the applicable guidelines for the Business Unit/Function for which they have applied. -EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsSan Diego, CAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Keywords: Takeda Pharmaceutical, Encinitas , Scientist, Computational Chemistry, Other , Encinitas, California